Latest News on Aloe Vera : May 21

[1] Aloe vera

We review the scientific literature regarding the aloe vera plant and its products. Aloe vera is known to contain several pharmacologically active ingredients, including a carboxypeptidase that inactivates bradykinin in vitro, salicylates, and a substance(s) that inhibits thromboxane formation in vivo. Scientific studies exist that support an antibacterial and antifungal effect for substance(s) in aloe vera. Studies and case reports provide support for the use of aloe vera in the treatment of radiation ulcers and stasis ulcers in man and burn and frostbite injuries in animals. The evidence for a potential beneficial effect associated with the use of aloe vera is sufficient to warrant the design and implementation of well-controlled clinical trials.


Aloe vera is a natural product that is now a day frequently used in the field of cosmetology. Though there are various indications for its use, controlled trials are needed to determine its real efficacy. The aloe vera plant, its properties, mechanism of action and clinical uses are briefly reviewed in this article.

[3] Aloe vera: a systematic review of its clinical effectiveness

The use of aloe vera is being promoted for a large variety of conditions. Often general practitioners seem to know less than their patients about its alleged benefits. AIM: To define the clinical effectiveness of aloe vera, a popular herbal remedy in the United Kingdom. METHOD: Four independent literature searches were conducted in MEDLINE, EMBASE, Biosis, and the Cochrane Library. Only controlled clinical trials (on any indication) were included. There were no restrictions on the language of publication. All trials were read by both authors and data were extracted in a standardized, pre-defined manner. RESULTS: Ten studies were located. They suggest that oral administration of aloe vera might be a useful adjunct for lowering blood glucose in diabetic patients as well as for reducing blood lipid levels in patients with hyperlipidaemia. Topical application of aloe vera is not an effective preventative for radiation-induced injuries. It might be effective for genital herpes and psoriasis. Whether it promotes wound healing is unclear. There are major caveats associated with all of these statements. CONCLUSION: Even though there are some promising results, clinical effectiveness of oral or topical aloe vera is not sufficiently defined at present.

[4] In-vitro Propagation of Aloe vera (L.) Burm. f

Aim: In vitro culture is used for commercial production and is achieved in aseptic condition using different concentration and combination of Plant Growth Regulators (PGR).

Material and Methods: In present work studied the effects of different plant growth regulator singly or in combination in tissue culture of Aloe vera (L.) Burm. f. belongs to the family Liliaceae or Asphodelaceae, used in ayurveda as well as pharmaceutical industry. Murashige and Skoog (MS) media with different combinations and concentration of growth promoters i.e. Auxin (Indole-3-butyric acid (IBA), α-Naphthalene acetic acid (NAA) and Indole-3-acetic acid (IAA) and cytokinin (Benzyl Amino Purine (BAP) were used in this study. Surface sterilization was standardised with HgCl2 with various concentration and time.

Observation and Result: The development of callus type was observed in the MS media supplemented with BAP for best regeneration, IBA for root formation and NAA, was found the best media for root formation (0.5mg/l) were seen to grow onwards from the tenth day of culture and 90% of root formation took place within a span of 3-4 weeks for maximum callus induction. The maximum number of root & shoot produced is 4.8±0.53 with average length of 3.5±0.35cm.

Discussion: The present work deals with in vitro plant growth of Aloe vera through tissue culture for propagation and ex situ conservation. Regenerated plants after acclimatization were transferred to soil and they showed 85% survival. The culture response was maximum in apical buds (100%) and minimum time required is 9.67 days in the same media. The average length of shoots per culture was 4.0±0.16cm. In present study among the three types of auxins, NAA was found to be the best for root induction.


[5] Aloe vera and Probiotics: A New Alternative to Symbiotic Functional Foods

Providing products that beyond a high nutritional value brings health benefits to consumers is a major challenge to food industry. Functional foods, including prebiotics and probiotic as components, are the protagonists to promote these advantages. Aloe vera is a medicinal plant well characterized in terms of its chemical composition and therapeutic properties. Taking into account these characteristics Aloe vera represents an excellent natural source of prebiotics, as well as a substrate for lactic acid bacteria fermentation. Thus a symbiotic drink using Aloe vera as the main ingredient and lactic acid bacteria as probiotics with significant benefits to human health might represent a promising product to develop.



[1] Klein, A.D. and Penneys, N.S., 1988. Aloe vera. Journal of the American Academy of Dermatology18(4), pp.714-720.

[2] Surjushe, A., Vasani, R. and Saple, D.G., 2008. Aloe vera: a short review. Indian journal of dermatology53(4), p.163.

[3] Vogler, B.K. and Ernst, E., 1999. Aloe vera: a systematic review of its clinical effectiveness. British journal of general practice49(447), pp.823-828.

[4] Gupta, S., Sahu, P.K., Sen, D.L. and Pandey, P., 2014. In-vitro propagation of aloe vera (L.) burm. f. Biotechnology Journal International, pp.806-816.

[5] Cuvas-Limón, R.B., Julio, M.S., Carlos, C.E.J., Mario, C.H., Mussatto, S.I. and Ruth, B.C., 2016. Aloe vera and probiotics: a new alternative to symbiotic functional foods. Annual Research & Review in Biology, pp.1-11.

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