Category: CHEMISTRY

New metal complexes as potential therapeutics The many activities of metal ions in biology have stimulated the development of metal-based therapeutics. Cisplatin, as one of the leading metal-based drugs, is widely used in treatment of cancer, being especially effective against genitourinary tumors such as testicular. Significant side effects and drug resistance, however, have limited its clinical applications. Biological carriers conjugated to cisplatin analogs have improved specificity for tumor tissue, thereby reducing side effects and drug resistance. Platinum complexes with distinctively … Continue reading “Latest Research on Metal Complexes : Feb 2022”

Distributed polarizabilities A new method has been developed for describing the response of a molecule to an external electric field. The molecule is divided into regions, and the charge, dipole, quadrupole etc. of each region are modified by the applied potential, electric field, field gradient etc. in the several regions. The method makes it possible to describe more accurately the response to a strongly non-uniform external field (such as the field due to a nearby ion or polar molecule) and … Continue reading “Latest Research on Polarizabilities : Jan 2022”

Phenyl-substituted polyquinoxalines Four phenyl-substituted polyquinoxalines have been prepared by the reaction of combinations of two tetraamines, 3,3′-diaminobenzidine and 3,3,′4,4′-tetraaminodiphenyl ether, with two bisbenzils, 4,4′-dibenzil and 4,4′-oxydibenzil. The polymers were prepared by melt and solution polymerizations. Melt condensations were performed at 180, 220, and 280°C. and samples were periodically removed and characterized. The solution polymerizations consisted of two stages, initially forming an intermediate molecular weight polymer (ηinh 0.6–1.0) which was advanced at 400°C. to final polymer (ηinh 1.5 to 2.2). Clear … Continue reading “Latest Research on phenyl : Jan 2022”

Bromide in the Natural Environment: Occurrence and Toxicity Bromide ion is widely used as a tracer to study water and solute transport because it does not adsorb to negatively charged soil minerals. Therefore is moves approximately as fast as water in soil. This property and the small natural background concentration make Br− an ideal tracer. It is much better than Cl−, which behaves similarly, but which is ubiquitous in the environment. Since Cl− is a component of several fertilizers, it … Continue reading “Latest Research on Bromide : Jan 2022”