Press Release on Pharmaceutical Research: August-2018

Pharmaceutical Waste Seeping into Environment

Muscle relaxants, opioids, and different prescription drugs area unit unseaworthy into the setting at 2 waste matter plants in big apple, a brand new study has disclosed.

Water coming into the streams from 2 waste matter treatment plants that area unit speculated to break down pharmaceutical producing waste had concentrations of prescription drugs between ten to one,000 times above water free into the setting from twenty four different plants across the state that don’t receive pharmaceutical waste, in keeping with the study, that is elaborate within the Gregorian calendar month four edition of the journal biological science and Technology. [1]

Medication Errors and Healthcare Uncertainty: Implications for Pharmaceutical Care in Two Tertiary Hospitals

Medication errors and uncertainty square measure of nice concern to health professionals thanks to their prevalence and impact on therapeutic outcomes. The objectives of the study square measure to explore pharmacists’ views of the relationships between medication errors and tending uncertainty; and their effects on pharmaceutical care and therapeutic outcomes in 2 tertiary hospitals in urban center, Nigeria.

A 17-item inventory was administered to pharmacists to elicit their views of prescribing, dispensing, and medicine body errors within the several skilled teams within the 2 hospitals. The context of ‘uncertainty’ was given to participants to avoid ambiguity of response. Section A was on demographics, Section B contains 3 queries every, on prescribing, dispensing and administration errors respectively; section C is on pharmacists’ interventions, patient safety and outcomes. The instrument was valid. Descriptive statistics, correlation and regression analyses, further as path analyses were wont to analyze the results. [2]

Electrochemical treatment of pharmaceutical wastewater through electrosynthesis of iron hydroxides for practical removal of metronidazole

Antibiotics because the severe contaminants of binary compound environments were received growing attention throughout the last decades. this work is that the 1st report on investigation the efficiency and potency of electrocoagulation method within the prospering removal of Flagyl (MNZ) from pharmaceutical effluent exploitation response surface methodology supported central composite style. The applied methodology by optimizing the freelance and combined effects of great variables that moving the global organization method increased the removal potency of MNZ. Analysis of variance was applied to verify the importance of freelance variables entirely and their interactions. the simplest removal potency of one hundred found below the optimum operational condition of initial MNZ concentration twenty one.6 mg L−1, pH 8.2, current density vi.0 mA cm−2, inter-electrode distance 3 cm, and interval of fourteen.6 min. isogram investigations unconcealed that the chemist model with the R2 of zero.994 best fitted to the obtained experimental equilibrium results. [3]

The Texture of Psychoactive Illicit Drugs in Iran: Adulteration with Lead and other Active Pharmaceutical Ingredients

Psychoactive illicit medicine area unit wide used everywhere the globe. thanks to the high demand for illicit medicine, adulteration of drugs with toxic and active pharmaceutical ingredients could be a common development in some countries. Lead and alternative active pharmaceutical ingredients area unit among adulterants extra to illicit medicine by design. within the gift study, we tend to analyzed four major abused street medicine in Iran’s drug black market (opium, Iranian crack, ecstasy tablets, and crystal methamphetamine) to assess active pharmaceutical ingredients and verify a quantitative assay of lead. a complete of forty psychedelic medicine were analyzed victimization superior liquid natural process, gas chromatography/mass spectrum analysis, and flame atomic absorption qualitative analysis. The results incontestable  that psychedelic medicine were adulterate with completely different drug classes, akin to tramadol, ketamine, methadone, analgesic, and alkaloid. Lead was found all told analyzed samples, starting from 9–90 ppm. [4]

Pharmaceutical Quality Analysis of Ceftriaxone Sodium Brands Marketed in Southern Nigeria

One of the preponderating controversies between Physicians and Pharmacists is that the issue of generic substitution. Prescribers ar compelled to settle on from such an outsized vary of brands. the target of this study was to check the Pharmaceutical quality of groundbreaker complete of injectable Mefoxin atomic number 11 with its generic brands that ar marketed in Southern Nigeria. Seven brands of injectable Mefoxin atomic number 11 marketed in some pharmacies in Southern Nigeria were analysed. normal physical and chemical tests for internal control of parenterals approved by Brits aggregation were performed on the branded sampled. [5]

Reference

[1] Pharmaceutical Waste Seeping into Environment

[2] Medication Errors and Healthcare Uncertainty: Implications for Pharmaceutical Care in Two Tertiary Hospitals

ANYIKA EN. Medication Errors and Healthcare Uncertainty: Implications for Pharmaceutical Care in Two Tertiary Hospitals. (web link)

[3] Electrochemical treatment of pharmaceutical wastewater through electrosynthesis of iron hydroxides for practical removal of metronidazole

Ahmadzadeh S, Dolatabadi M. Electrochemical treatment of pharmaceutical wastewater through electrosynthesis of iron hydroxides for practical removal of metronidazole. Chemosphere. 2018 Aug 22. (web link)

[4] The Texture of Psychoactive Illicit Drugs in Iran: Adulteration with Lead and other Active Pharmaceutical Ingredients

Akhgari M, Moradi F, Ziarati P. The Texture of Psychoactive Illicit Drugs in Iran: Adulteration with Lead and other Active Pharmaceutical Ingredients. Journal of psychoactive drugs. 2018 Aug 20:1-9. (web link)

[5] Pharmaceutical Quality Analysis of Ceftriaxone Sodium Brands Marketed in Southern Nigeria

Ogbonna Okorie1, E. Omotoso Abayomi2* and Ebinyansi Onyinyechi1

1Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, University of Port Harcourt, Rivers State, Nigeria.

2Department of Pharmaceutical and Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Port Harcourt, Rivers State, Nigeria. (web link)

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