News Update on Ethyl Acetate Extracts Research: Sep – 2019

Antimutagenic, antioxidant and free radical scavenging activity of ethyl acetate extracts from white, yellow and red onions

The useful effects of red, yellow and white onion extracts are assessed by inhibitor activity and antimutagenic activity. and therefore the effects compared to BHT and vitamin C. Total synthetic resin compounds and flavonoids in onion extracts were determined. Yellow onion extract had additional organic acid and free sugar than those detected within the white and purple onion extract. The scavenging activity of DPPH radical and H2O2 were exaggerated counting on the concentration. The inhibitor activities mistreatment β-carotene-linoleate system and reducing power were exaggerated however the impact was tiny thereto of BHT and vitamin C. once digestible, extracts showed antimutagenic activities, and it appears that they inhibit the mutagenicity for digesting. [1]

Enhancement of polysaccharides production in Ganoderma lucidum by the addition of ethyl acetate extracts from Eupolyphaga sinensis and Catharsius molossus

To screen stimulators from Chinese healthful insects for mycelial growth and polysaccharides production of Ganoderma lucidum, G. lucidum was inoculated into the media with and while not supplementation of healthful insect extracts. The ester extract of Eupolyphaga sinensis at fifty five mg l−1 result in important increase in each biomass and animate thing polysaccharides (IPS) concentration from eight.53 ± 0.41 to 14.16 ± 0.43 and 1.28 ± 0.09 to 2.13 ± 0.11 g l−1, severally. additionally, the ester extract of Catharsius molossus at fifty five mg l−1 considerably increased living thing polysaccharides (EPS) production; the EPS yield enhanced from 350.9 ± 14.1 to 475.1 ± 15.3 mg l−1. there have been no new parts within the 2 kinds of polysaccharides obtained by the addition of the insect extracts. [2]

Ethyl acetate extracts of alfalfa (Medicago sativa L.) sprouts inhibit lipopolysaccharide-induced inflammation in vitro and in vivo

This study aimed to research if food elements that exert medicine effects is also used for inflammatory disorders by examining sprout ester extract (ASEA). The protein profile and lifetime of BALB/c mice with acute inflammation once intra-peritoneal (ip) injection of fifteen mg/kg bioattack lipopolysaccharide (LPS) were determined. The results showed that the lifetime of LPS-induced inflammatory mice were negatively related  with bodily fluid levels of TNF-α, IL-6, and IL-1β at nine hour once LPS-injection, that indicated that suppressing these cytokines within the late section of inflammation is also helpful for survival. The in vitro experiment then showed that toward the sea considerably reduced IL-6 and IL-1β production and therefore the NF-κB trans-activation activity of mitogen-stimulated RAW264.7 cells. [3]

Chemical constituents and anti-inflammatory activities of Maqian (Zanthoxylum myriacanthum var. pubescens) bark extracts

In this study, forty four compounds within the crude oil ether extract of Maqian (Zanthoxylum myriacanthum power unit. pubescens) bark, a conventional Dai flavorer drugs, were known by GC-MS. Major parts enclosed 3(2H)-benzofuranone, asarinin and (dimethoxymethyl)-3-methoxy-benzene. a complete of eighteen compounds were isolated from the ester extracts of Maqian bark by chromatography and known by chemical and spectral analyses. Rhoifoline B, zanthoxyline dimethoxy spinoff, N-nortidine, nitidine, decarine are the most important alkaloids. each the crude oil ether and ester extracts showed vital inhibition on NO production, that imply medicament activity, in lipopolysaccharide-induced RAW 264.7 cells while not cell toxicity. [4]

Anti-inflammatory Activity of Hexane and Ethyl Acetate Extracts of Hura crepitans L.

Aims: the current analysis aimed to guage the medicinal drug action of dissolver and ester extracts of Hura crepitans L. (Euphorbiaceae) full-grown in Federal Republic of Nigeria

Study Design:  The study involves the extraction of crude extracts from the leaf of H. crepitans and therefore the analysis of their medicinal drug potential.

Place and period of Study: recent leaves of H. crepitans were collected from Festac city, Amuwo-Odofin in port, Nigeria (6.4664oN, 3.2835oE). The sheets were dry within the laboratory of port State University wherever the extraction of crude and anti inflammatory studies befell. The study lasted between March and Nov 2017. [5]

Reference

[1] Shon, M.Y., Choi, S.D., Kahng, G.G., Nam, S.H. and Sung, N.J., 2004. Antimutagenic, antioxidant and free radical scavenging activity of ethyl acetate extracts from white, yellow and red onions. Food and Chemical Toxicology, 42(4), (Web Link)

[2] Liu, G.Q. and Zhang, K.C., 2007. Enhancement of polysaccharides production in Ganoderma lucidum by the addition of ethyl acetate extracts from Eupolyphaga sinensis and Catharsius molossus. Applied microbiology and biotechnology, 74(3), (Web Link)

[3] Hong, Y.H., Chao, W.W., Chen, M.L. and Lin, B.F., 2009. Ethyl acetate extracts of alfalfa (Medicago sativa L.) sprouts inhibit lipopolysaccharide-induced inflammation in vitro and in vivo. Journal of Biomedical Science, 16(1), (Web Link)

[4] Chemical constituents and anti-inflammatory activities of Maqian (Zanthoxylum myriacanthum var. pubescens) bark extracts
Huan-li Zhang, Xiao-qing Gan, Qing-fei Fan, Jing-jing Yang, Ping Zhang, Hua-bin Hu & Qi-shi Song
Scientific Reports volume7, Article number: 45805 (2017) (Web Link)

[5] N. Avoseh, O., Ogunbajo, L. O., Ogunwande, I. A., L. Ogundajo, A. and A. Lawal, O. (2018) “Anti-inflammatory Activity of Hexane and Ethyl Acetate Extracts of Hura crepitans L.”, European Journal of Medicinal Plants, 24(1), (Web Link)

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