News Update on Aspergillus Niger Research: Dec – 2019

Ochratoxin A production by strains of Aspergillus niger var. niger.

In a survey of the occurrence of ochratoxin A (OA)-positive strains isolated from feedstuffs, two of the 19 isolates of Aspergillus niger var. niger that were studied produced OA in 2% yeast extract-15% sucrose broth and in corn cultures. this is often the primary report of production of OA by this species. [1]

On the safety of Aspergillus niger – a review

Aspergillus niger is one among the foremost important microorganisms utilized in biotechnology. it’s been in use already for several decades to supply extracellular (food) enzymes and acid. In fact, acid and lots of A. niger enzymes are considered GRAS by the us Food and Drug Administration. additionally, A. niger is employed for biotransformations and waste treatment. within the last 20 years, A. niger has been developed as a crucial transformation host to over-express food enzymes. Being pre-dated by older names, the name A. niger has been conserved for economical and knowledge retrieval reasons and there’s a taxonomical consensus supported molecular data that the sole other common species closely associated with A. [2]

Removal of heavy metals using the fungus Aspergillus niger

There is a requirement to develop technologies which will remove toxic heavy metal ions found in wastewaters. Microorganisms are known to get rid of heavy metal ions from water. during this study the potential of the fungus Aspergillus niger to get rid of lead, cadmium, copper and nickel ions was evaluated. A. niger biomass pretreated by boiling in 0.1N NaOH solution for 15 min exhibited higher lead, cadmium and copper removal capacities than did live biomass. Live A. niger biomass was found to be simpler within the removal of nickel than biomass which had been boiled in 0.1N NaOH solution for 15 min. The pH of the answer strongly affected the degree of biosorption of heavy metal ions on biomass pretreated by boiling in 0.1N NaOH solution. [3]

Aspergillus fumigatus establishes infection in zebrafish by germination of phagocytized conidia, while Aspergillus niger relies on extracellular germination

Among opportunistically pathogenic filamentous fungi of the Aspergillus genus, Aspergillus fumigatus stands out as a drastically more prevalent explanation for infection than others. Utilizing the zebrafish embryo model, we applied a mixture of non-invasive real-time imaging and genetic approaches to match the infectious development of A. fumigatus thereupon of the less pathogenic A. niger. We found that both species evoke similar immune cell migratory responses, but A. fumigatus is more efficiently phagocytized than A. niger. [4]

Antibacterial Potential of Magnesium Oxide Nanoparticles Synthesized by Aspergillus niger

A total of 280 tract infection samples were collected during this investigation. Out of them 212(75.7%) samples showed a positive response.to bacterial isolates. Morphological, cultural and biochemical testes were confirmed using VITEK 2 System. Its revealed that 54 (30.2%) of the bacterial isolates were gram positive and 158 (69.8%) gram negative. The bacterial isolates were distributed as Escherichia coli 96 (45.2%), followed by Klebsiella pneumonia 48 (22.6%), Staphylococcus aureus 43(20.3%), Pseudomonas aeruginosa 14 (6.6%), and Staphylococcus epidermidis 11 (5.2%). The synthesis of periclase nanoparticles (MgO NPs) was performed using Aspergillus niger Method. Agar Wells Diffusion Method was applied for the evaluation of antibacterial activity against gram positive S. [5]

Reference

[1] Abarca, M.L., Bragulat, M.R., Castella, G. and Cabanes, F.J., 1994. Ochratoxin A production by strains of Aspergillus niger var. niger. Appl. Environ. Microbiol., 60(7), (Web Link)

[2] Schuster, E., Dunn-Coleman, N., Frisvad, J.C. and Van Dijck, P.W., 2002. On the safety of Aspergillus niger–a review. Applied microbiology and biotechnology, 59(4-5), (Web Link)

[3] Kapoor, A., Viraraghavan, T. and Cullimore, D.R., 1999. Removal of heavy metals using the fungus Aspergillus niger. Bioresource technology, 70(1), (Web Link)

[4] Aspergillus fumigatus establishes infection in zebrafish by germination of phagocytized conidia, while Aspergillus niger relies on extracellular germination
Bjørn E. V. Koch, Natalia H. Hajdamowicz, Ellen Lagendijk, Arthur F. J. Ram & Annemarie H. Meijer
Scientific Reports volume 9, (Web Link)

[5] J. Ibrahem, E., M. Thalij, K. and S. Badawy, A. (2017) “Antibacterial Potential of Magnesium Oxide Nanoparticles Synthesized by Aspergillus niger”, Biotechnology Journal International, 18(1), (Web Link)

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