NEWS UPDATE ON ALOE VERA: FEB – 2020

The Aloe vera phenomenon: A review of the properties and modern uses of the leaf parenchyma gel

The mucilaginous gel from the parenchymatous cells in the leaf pulp of Aloe vera has been used since early times for a host of curative purposes. This gel should be distinguished clearly from the bitter yellow exudate originating from the bundle sheath cells, which is used for its purgative effects. Aloe vera gel has come to play a prominent role as a contemporary folk remedy, and numerous optimistic, and in some cases extravagant, claims have been made for its medicinal properties. [1]

 

Anti-inflammatory and wound healing activity of a growth substance in Aloe vera.

Aloe vera improves wound healing and inhibits inflammation. Since mannose-6-phosphate is the major sugar in the Aloe gel, the authors examined the possibility of its being an active growth substance. Mice receiving 300 mg/kg of mannose-6-phosphate had improved wound healing over saline controls. This dose also had anti-inflammatory activity. The function of mannose-6-phosphate in A. vera is discussed. [2]

Influence of Aloe vera on collagen characteristics in healing dermal wounds in rats

Wound healing is a fundamental response to tissue injury that results in restoration of tissue integrity. This end is achieved mainly by the synthesis of the connective tissue matrix. Collagen is the major protein of the extracellular matrix, and is the component which ultimately contributes to wound strength. In this work, we report the influence of Aloe vera on the collagen content and its characteristics in a healing wound. [3]

Aloe vera and Probiotics: A New Alternative to Symbiotic Functional Foods

Providing products that beyond a high nutritional value brings health benefits to consumers is a major challenge to food industry. Functional foods, including prebiotics and probiotic as components, are the protagonists to promote these advantages. Aloe vera is a medicinal plant well characterized in terms of its chemical composition and therapeutic properties. Taking into account these characteristics Aloe vera represents an excellent natural source of prebiotics, as well as a substrate for lactic acid bacteria fermentation. Thus a symbiotic drink using Aloe vera as the main ingredient and lactic acid bacteria as probiotics with significant benefits to human health might represent a promising product to develop. [4]

Assessment of the effect of Watermelon and Aloe Vera on Cadmium Induced Heart Damage in Adult Wistar Rats (Rattus novergicus)

The aim of the study was to investigate the antioxidant property of watermelon and aloe vera against cadmium damaging effect on the heart and the packed cell volume of the blood. Thirty five Wistar rats were obtained and acclimatized for two weeks. They were randomly divided into 7 groups, five rats each. Animal in individual groups were induced intraperitoneally with 3.0 mg/kg of cadmium sulphate and were treated with aloe vera and water melon at 40 mg/kg, animals in control group received 3.0 mg/kg of PBS as shown in Table 1. The research lasted for 4 weeks. The enzymes analysis on antioxidant activity and packed cell volume was considered statistically significant at (p<0.05) based on Mean±SEM. The packed cell volume significantly increased for watermelon group 5 and aloe vera group 6 when compared to normal control group 1. Group 3, 6 and 7 were statistically significant when compared to the mean value of the normal control while group 4 and 5 were not statistically significant for Malondialdehyde (MDA), Catalase (CAT) and Glutathione peroxidase (GPx). None was statistically significant for Superoxide Dismutase (SOD). Group 2, 3, 4, 6 and 7 were statistically significant for acetylcholinesterase (AChE). The results from this experiment demonstrate the high degree of potency in aloe vera over watermelon in preventing oxidative damage due to cadmium interaction with the animal system. [5]

 

Reference

[1] Grindlay, D. and Reynolds, T., 1986. The Aloe vera phenomenon: a review of the properties and modern uses of the leaf parenchyma gel. Journal of ethnopharmacology16(2-3), pp.117-151.

[2]  Davis, R.H., Donato, J.J., Hartman, G.M. and Haas, R.C., 1994. Anti-inflammatory and wound healing activity of a growth substance in Aloe vera. Journal of the American Podiatric Medical Association84(2), pp.77-81.

[3]  Chithra, P., Sajithlal, G.B. and Chandrakasan, G., 1998. Influence of Aloe vera on collagen characteristics in healing dermal wounds in rats. Molecular and cellular biochemistry181(1-2), pp.71-76.

[4] Cuvas-Limón, R.B., Julio, M.S., Carlos, C.E.J., Mario, C.H., Mussatto, S.I. and Ruth, B.C., 2016. Aloe vera and probiotics: a new alternative to symbiotic functional foods. Annual Research & Review in Biology, pp.1-11.

[5] Omotoso, O.D., Adelakun, S.A., Akpan, H.B., Yusuf, U.A., Adeleye, O.O. and Adeyinka, O.O., 2016. Assessment of the effect of Watermelon and Aloe Vera on Cadmium Induced Heart Damage in Adult Wistar Rats (Rattus novergicus). Cardiology and Angiology: An International Journal, pp.1-9.

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